Die therapie des antiphospholipid syndroms besteht in der therapie der thrombotisch embolisch hervorgerufenen ereignisse dh einer antikoagulation bei thrombosen bzw der therapie eines myokardinfarktes oder eines schlaganfalls. The antiphospholipid syndrome aps is an autoimmune thrombophilic condition that is marked by the presence of antibodies that recognize phospholipid binding proteins the clinical manifestations of aps include vascular thrombosis and pregnancy complications especially recurrent spontaneous miscarriages this article provides an update on diagnostic and therapeutic approaches to this disorder